If you’re DataStores are using Fibre channel storage and you have multple fchba’s connected through to the SAN via a fc switch or two, then it is prudent to optimise the IO potential of all the redundant hardware by changing the fc path policy to “round robin”.
Using vsphere client, connect to the ESXi host / vcentre server
Inventory, Hosts and Clusters, select ESXi host
Configuration tab, Storage, highlight the datastore, click Properties
Click Manage Paths button on the DataStore properties dialog
Change Path Selection to Round Robin (VMWARE) – the default is Most Recently Used (VMWARE)
Wait for the screen to reload, Click Close
Repeat for each DataStore, and then Repeat for each ESXi host.